CG9635-RB RhoGEF2 FBgn0023172 GO:0000902 cellular morphogenesis*GO:0003674 molecular_function*GO:0005083 small GTPase regulatory/interacting protein activity*GO:0005085 guanyl-nucleotide exchange factor activity*GO:0005089 Rho guanyl-nucleotide exchange factor activity*GO:0005488 binding*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006897 endocytosis*GO:0006909 phagocytosis*GO:0006915 apoptosis*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007049 cell cycle*GO:0007154 cell communication*GO:0007155 cell adhesion*GO:0007165 signal transduction*GO:0007275 development*GO:0007369 gastrulation*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008219 cell death*GO:0008283 cell proliferation*GO:0008289 lipid binding*GO:0008360 regulation of cell shape*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009987 cellular process*GO:0012501 programmed cell death*GO:0015031 protein transport*GO:0016043 cell organization and biogenesis*GO:0016192 vesicle-mediated transport*GO:0016265 death*GO:0016476 shape changes of embryonic cells*GO:0019992 diacylglycerol binding*GO:0030234 enzyme regulator activity*GO:0030695 GTPase regulator activity*GO:0046907 intracellular transport*GO:0050789 regulation of biological process*GO:0050794 regulation of cellular process*GO:0050875 cellular physiological process* REAL 17.89 17.89 1 CG30497-RA - FBgn0050497 - REAL 17.26 17.26 1 CG12946-RA - FBgn0037750 - REAL 17.26 17.26 1 CG4001-RA Pfk FBgn0003071 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0003872 6-phosphofructokinase activity*GO:0005975 carbohydrate metabolism*GO:0005996 monosaccharide metabolism*GO:0006006 glucose metabolism*GO:0006007 glucose catabolism*GO:0006066 alcohol metabolism*GO:0006091 energy pathways*GO:0006092 main pathways of carbohydrate metabolism*GO:0006096 glycolysis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008443 phosphofructokinase activity*GO:0009056 catabolism*GO:0015980 energy derivation by oxidation of organic compounds*GO:0016052 carbohydrate catabolism*GO:0016301 kinase activity*GO:0016740 transferase activity*GO:0016772 transferase activity, transferring phosphorus-containing groups*GO:0016773 phosphotransferase activity, alcohol group as acceptor*GO:0019200 carbohydrate kinase activity*GO:0019318 hexose metabolism*GO:0019320 hexose catabolism*GO:0043170 macromolecule metabolism*GO:0046164 alcohol catabolism*GO:0046365 monosaccharide catabolism*KEGG:1.1 Glycolysis / Gluconeogenesis*KEGG:1.3 Pentose phosphate pathway*KEGG:1.5 Fructose and mannose metabolism*KEGG:1.6 Galactose metabolism* REAL 16.91 16.91 1 CG7112-RA - FBgn0035879 GO:0000067 DNA replication and chromosome cycle*GO:0000087 M phase of mitotic cell cycle*GO:0000278 mitotic cell cycle*GO:0000279 M phase*GO:0000280 nuclear division*GO:0003674 molecular_function*GO:0005083 small GTPase regulatory/interacting protein activity*GO:0005096 GTPase activator activity*GO:0005097 Rab GTPase activator activity*GO:0006810 transport*GO:0007049 cell cycle*GO:0007059 chromosome segregation*GO:0007067 mitosis*GO:0007582 physiological process*GO:0008047 enzyme activator activity*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008283 cell proliferation*GO:0009987 cellular process*GO:0030234 enzyme regulator activity*GO:0030695 GTPase regulator activity*GO:0050875 cellular physiological process* REAL 16.91 16.91 1 CG11748-RA Obp19a FBgn0031109 GO:0003674 molecular_function*GO:0005488 binding*GO:0005549 odorant binding* PRED 16.79 16.79 1 CG4196-RC - FBgn0038297 GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0005057 receptor signaling protein activity* REAL 16.73 16.73 1 CG1322-RB zfh1 FBgn0004606 GO:0000003 reproduction*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0003702 RNA polymerase II transcription factor activity*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005634 nucleus*GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0006350 transcription*GO:0006351 transcription, DNA-dependent*GO:0006355 regulation of transcription, DNA-dependent*GO:0006357 regulation of transcription from Pol II promoter*GO:0006366 transcription from Pol II promoter*GO:0006928 cell motility*GO:0007275 development*GO:0007276 gametogenesis*GO:0007398 ectoderm development*GO:0007399 neurogenesis*GO:0007417 central nervous system development*GO:0007498 mesoderm development*GO:0007507 heart development*GO:0007517 muscle development*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008354 germ cell migration*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0009888 histogenesis*GO:0009987 cellular process*GO:0016477 cell migration*GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0019222 regulation of metabolism*GO:0019953 sexual reproduction*GO:0030528 transcription regulator activity*GO:0045449 regulation of transcription*GO:0050789 regulation of biological process*GO:0050791 regulation of physiological process*GO:0050875 cellular physiological process*JU:0007399 transcription + neurogenesis*JU:0009888 transcription + histogenesis*JU:0007517 transcription + muscle development*JU:0007507 transcription + heart development* REAL 16.73 16.73 1 CG32836-RA - FBgn0052836 - PRED 16.62 16.62 1 CG30069-RA - FBgn0050069 GO:0000074 regulation of cell cycle*GO:0007049 cell cycle*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008283 cell proliferation*GO:0009987 cellular process*GO:0050875 cellular physiological process* REAL 16.56 16.56 1 CG13693-RA - FBgn0031235 - PRED 15.86 15.86 1 CG12378-RA - FBgn0038748 - PRED 14.99 14.99 1 CG2909-RA - FBgn0030189 - REAL 14.29 14.29 1 CG14330-RA - FBgn0038512 - REAL 14.29 14.29 1 CG5226-RA - FBgn0034355 GO:0003674 molecular_function*GO:0005215 transporter activity*GO:0006810 transport*GO:0006811 ion transport*GO:0006858 extracellular transport*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009987 cellular process*GO:0050875 cellular physiological process* REAL 13.64 13.64 1 CG31776-RA - FBgn0051776 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity*GO:0005975 carbohydrate metabolism*GO:0005976 polysaccharide metabolism*GO:0006412 protein biosynthesis*GO:0006464 protein modification*GO:0006486 protein amino acid glycosylation*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008376 acetylgalactosaminyltransferase activity*GO:0009058 biosynthesis*GO:0009059 macromolecule biosynthesis*GO:0009100 glycoprotein metabolism*GO:0009101 glycoprotein biosynthesis*GO:0016740 transferase activity*GO:0016757 transferase activity, transferring glycosyl groups*GO:0016758 transferase activity, transferring hexosyl groups*GO:0019538 protein metabolism*GO:0043170 macromolecule metabolism* PRED 12.72 12.72 1 CG14642-RA - FBgn0037222 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004175 endopeptidase activity*GO:0004252 serine-type endopeptidase activity*GO:0004295 trypsin activity*GO:0006508 proteolysis and peptidolysis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008233 peptidase activity*GO:0008236 serine-type peptidase activity*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0016787 hydrolase activity*GO:0019538 protein metabolism*GO:0030163 protein catabolism*GO:0043170 macromolecule metabolism* REAL 12.65 12.65 1 CG8107-RA CalpB FBgn0025866 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004175 endopeptidase activity*GO:0004197 cysteine-type endopeptidase activity*GO:0004198 calpain activity*GO:0005488 binding*GO:0005509 calcium ion binding*GO:0005515 protein binding*GO:0005516 calmodulin binding*GO:0006508 proteolysis and peptidolysis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008233 peptidase activity*GO:0008234 cysteine-type peptidase activity*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0016787 hydrolase activity*GO:0019538 protein metabolism*GO:0030163 protein catabolism*GO:0043167 ion binding*GO:0043170 macromolecule metabolism*GO:0046872 metal ion binding* REAL 12.57 12.57 1 CG14864-RA - FBgn0038311 - PRED 12.50 12.50 1 CG4557-RA - FBgn0029912 GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0003700 transcription factor activity*GO:0005488 binding*GO:0030528 transcription regulator activity* PRED 12.42 12.42 1 CG7734-RA shn FBgn0003396 GO:0000122 negative regulation of transcription from Pol II promoter*GO:0001654 eye morphogenesis*GO:0001700 embryonic development (sensu Insecta)*GO:0001745 compound eye morphogenesis (sensu Drosophila)*GO:0002009 morphogenesis of an epithelium*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0003700 transcription factor activity*GO:0003702 RNA polymerase II transcription factor activity*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005634 nucleus*GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0006350 transcription*GO:0006351 transcription, DNA-dependent*GO:0006355 regulation of transcription, DNA-dependent*GO:0006357 regulation of transcription from Pol II promoter*GO:0006366 transcription from Pol II promoter*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway*GO:0007179 transforming growth factor beta receptor signaling pathway*GO:0007275 development*GO:0007389 pattern specification*GO:0007391 dorsal closure*GO:0007398 ectoderm development*GO:0007399 neurogenesis*GO:0007422 peripheral nervous system development*GO:0007431 salivary gland development*GO:0007432 salivary gland determination*GO:0007444 imaginal disc development*GO:0007447 imaginal disc pattern formation*GO:0007448 anterior/posterior pattern formation, imaginal disc*GO:0007452 imaginal disc metamorphosis*GO:0007455 eye-antennal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007472 wing disc metamorphosis*GO:0007476 wing morphogenesis*GO:0007494 midgut development*GO:0007552 metamorphosis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008283 cell proliferation*GO:0008586 wing vein morphogenesis*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009795 embryonic morphogenesis*GO:0009887 organogenesis*GO:0009888 histogenesis*GO:0009892 negative regulation of metabolism*GO:0009952 anterior/posterior pattern formation*GO:0009987 cellular process*GO:0016331 morphogenesis of embryonic epithelium*GO:0016481 negative regulation of transcription*GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0019222 regulation of metabolism*GO:0030528 transcription regulator activity*GO:0035107 appendage morphogenesis*GO:0035114 appendage morphogenesis (sensu Holometabola)*GO:0045449 regulation of transcription*GO:0045704 regulation of salivary gland determination*GO:0045705 negative regulation of salivary gland determination*GO:0045892 negative regulation of transcription, DNA-dependent*GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0046698 metamorphosis (sensu Insecta)*GO:0048100 wing disc anterior/posterior pattern formation*GO:0050789 regulation of biological process*GO:0050791 regulation of physiological process*GO:0050875 cellular physiological process*JU:0007399 transcription + neurogenesis*JU:0007431 transcription + salivary gland development*JU:0009888 transcription + histogenesis*JU:0007494 transcription + midgut development*JU:0007444 transcription + imaginal disc development*JU:0001654 transcription + eye morphogenesis* REAL 12.31 12.31 1 CG11136-RA - FBgn0034540 GO:0006952 defense response*GO:0007154 cell communication*GO:0007155 cell adhesion*GO:0007267 cell-cell signaling*GO:0007582 physiological process*GO:0008150 biological_process*GO:0009607 response to biotic stimulus*GO:0009987 cellular process*GO:0019226 transmission of nerve impulse*GO:0050874 organismal physiological process*GO:0050877 neurophysiological process*GO:0050879 organismal movement*GO:0050896 response to stimulus*GO:0050905 neuromuscular physiological process* PRED 12.04 12.04 1 CG14297-RA - FBgn0038655 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004721 phosphoprotein phosphatase activity*GO:0004725 protein tyrosine phosphatase activity*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0006464 protein modification*GO:0006470 protein amino acid dephosphorylation*GO:0006793 phosphorus metabolism*GO:0006796 phosphate metabolism*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0016311 dephosphorylation*GO:0016787 hydrolase activity*GO:0016788 hydrolase activity, acting on ester bonds*GO:0016791 phosphoric monoester hydrolase activity*GO:0019538 protein metabolism*GO:0042578 phosphoric ester hydrolase activity*GO:0043170 macromolecule metabolism* PRED 11.87 11.87 1 CG31035-RA - FBgn0051035 GO:0000004 biological_process unknown*GO:0003674 molecular_function*GO:0005554 molecular_function unknown*GO:0005575 cellular_component*GO:0008150 biological_process*GO:0008372 cellular_component unknown* PRED 11.73 11.73 1 CG14566-RA - FBgn0037127 - PRED 11.58 11.58 1 CG4408-RA - FBgn0039073 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004180 carboxypeptidase activity*GO:0004181 metallocarboxypeptidase activity*GO:0006508 proteolysis and peptidolysis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008233 peptidase activity*GO:0008235 metalloexopeptidase activity*GO:0008237 metallopeptidase activity*GO:0008238 exopeptidase activity*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0016787 hydrolase activity*GO:0019538 protein metabolism*GO:0030163 protein catabolism*GO:0043170 macromolecule metabolism* REAL 11.47 11.47 1 CG14333-RA - FBgn0038500 - PRED 11.45 11.45 1 CG10881-RA - FBgn0038796 GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003723 RNA binding*GO:0003743 translation initiation factor activity*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005852 eukaryotic translation initiation factor 3 complex*GO:0006412 protein biosynthesis*GO:0006413 translational initiation*GO:0007582 physiological process*GO:0008135 translation factor activity, nucleic acid binding*GO:0008150 biological_process*GO:0008152 metabolism*GO:0009058 biosynthesis*GO:0009059 macromolecule biosynthesis*GO:0016282 eukaryotic 43S preinitiation complex*GO:0019538 protein metabolism*GO:0043037 translation*GO:0043170 macromolecule metabolism*GO:0045182 translation regulator activity*KEGG:13.2 Translation factors* PRED 11.45 11.45 1 CG15660-RA - FBgn0034608 - PRED 11.24 11.24 1 CG31421-RA - FBgn0051421 GO:0000165 MAPKKK cascade*GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004672 protein kinase activity*GO:0004674 protein serine/threonine kinase activity*GO:0004702 receptor signaling protein serine/threonine kinase activity*GO:0004709 MAP kinase kinase kinase activity*GO:0004871 signal transducer activity*GO:0005057 receptor signaling protein activity*GO:0006464 protein modification*GO:0006468 protein amino acid phosphorylation*GO:0006793 phosphorus metabolism*GO:0006796 phosphate metabolism*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007242 intracellular signaling cascade*GO:0007243 protein kinase cascade*GO:0007254 JNK cascade*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0009987 cellular process*GO:0016301 kinase activity*GO:0016310 phosphorylation*GO:0016740 transferase activity*GO:0016772 transferase activity, transferring phosphorus-containing groups*GO:0016773 phosphotransferase activity, alcohol group as acceptor*GO:0019538 protein metabolism*GO:0043170 macromolecule metabolism* PRED 11.21 11.21 1 CG8865-RB Rgl FBgn0026376 GO:0003674 molecular_function*GO:0005083 small GTPase regulatory/interacting protein activity*GO:0005085 guanyl-nucleotide exchange factor activity*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0008150 biological_process*GO:0008321 Ral guanyl-nucleotide exchange factor activity*GO:0009987 cellular process*GO:0016219 GDP-dissociation stimulator activity*GO:0016220 RAL GDP-dissociation stimulator activity*GO:0030234 enzyme regulator activity*GO:0030695 GTPase regulator activity* REAL 10.94 10.94 1 CG8865-RC Rgl FBgn0026376 GO:0003674 molecular_function*GO:0005083 small GTPase regulatory/interacting protein activity*GO:0005085 guanyl-nucleotide exchange factor activity*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0008150 biological_process*GO:0008321 Ral guanyl-nucleotide exchange factor activity*GO:0009987 cellular process*GO:0016219 GDP-dissociation stimulator activity*GO:0016220 RAL GDP-dissociation stimulator activity*GO:0030234 enzyme regulator activity*GO:0030695 GTPase regulator activity* REAL 10.94 10.94 1 CG15278-RA - FBgn0032554 - PRED 10.83 10.83 1 CG13726-RA Or74a FBgn0036709 GO:0001584 rhodopsin-like receptor activity*GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0004872 receptor activity*GO:0004888 transmembrane receptor activity*GO:0004930 G-protein coupled receptor activity*GO:0004984 olfactory receptor activity*GO:0005575 cellular_component*GO:0005623 cell*GO:0007582 physiological process*GO:0007600 sensory perception*GO:0007606 sensory perception of chemical stimulus*GO:0007608 perception of smell*GO:0008150 biological_process*GO:0009581 detection of external stimulus*GO:0009605 response to external stimulus*GO:0016020 membrane*GO:0016021 integral to membrane*GO:0050874 organismal physiological process*GO:0050877 neurophysiological process*GO:0050896 response to stimulus* PRED 10.83 10.83 1 CG4722-RA bib FBgn0000180 GO:0000003 reproduction*GO:0003674 molecular_function*GO:0005215 transporter activity*GO:0005243 gap-junction forming channel activity*GO:0005386 carrier activity*GO:0005488 binding*GO:0005575 cellular_component*GO:0005623 cell*GO:0005886 plasma membrane*GO:0005887 integral to plasma membrane*GO:0005911 intercellular junction*GO:0005921 gap junction*GO:0005922 connexon complex*GO:0006810 transport*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007219 Notch signaling pathway*GO:0007275 development*GO:0007276 gametogenesis*GO:0007292 female gamete generation*GO:0007398 ectoderm development*GO:0007399 neurogenesis*GO:0007498 mesoderm development*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0009888 histogenesis*GO:0009987 cellular process*GO:0009993 oogenesis (sensu Insecta)*GO:0015267 channel or pore class transporter activity*GO:0015268 alpha-type channel activity*GO:0015285 connexon channel activity*GO:0016020 membrane*GO:0016021 integral to membrane*GO:0016327 apicolateral plasma membrane*GO:0019725 cell homeostasis*GO:0019953 sexual reproduction*GO:0030054 cell junction*GO:0030707 ovarian follicle cell development (sensu Insecta)*GO:0042592 homeostasis*GO:0048477 oogenesis*GO:0050875 cellular physiological process* REAL 10.70 10.70 1 CG5248-RD loco FBgn0020278 GO:0000003 reproduction*GO:0002009 morphogenesis of an epithelium*GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0005057 receptor signaling protein activity*GO:0005083 small GTPase regulatory/interacting protein activity*GO:0006810 transport*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0007275 development*GO:0007276 gametogenesis*GO:0007292 female gamete generation*GO:0007300 nurse cell to ocyte transport (sensu Insecta)*GO:0007303 cytoplasmic transport, nurse cell to oocyte*GO:0007389 pattern specification*GO:0007399 neurogenesis*GO:0007582 physiological process*GO:0008069 dorsal/ventral axis determination, follicular epithelium (sensu Insecta)*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008277 regulation of G-protein coupled receptor protein signaling pathway*GO:0009653 morphogenesis*GO:0009798 axis specification*GO:0009887 organogenesis*GO:0009950 dorsal/ventral axis specification*GO:0009953 dorsal/ventral pattern formation*GO:0009966 regulation of signal transduction*GO:0009987 cellular process*GO:0009993 oogenesis (sensu Insecta)*GO:0010001 glial cell differentiation*GO:0016299 regulator of G-protein signaling activity*GO:0016333 morphogenesis of follicular epithelium*GO:0016334 establishment and/or maintenance of polarity of follicular epithelium*GO:0016482 cytoplasmic transport*GO:0019953 sexual reproduction*GO:0030154 cell differentiation*GO:0030234 enzyme regulator activity*GO:0030695 GTPase regulator activity*GO:0030707 ovarian follicle cell development (sensu Insecta)*GO:0042063 gliogenesis*GO:0046907 intracellular transport*GO:0048477 oogenesis*GO:0050789 regulation of biological process*GO:0050794 regulation of cellular process*GO:0050875 cellular physiological process* REAL 10.70 10.70 1 CG11949-RC cora FBgn0010434 GO:0000902 cellular morphogenesis*GO:0001700 embryonic development (sensu Insecta)*GO:0002009 morphogenesis of an epithelium*GO:0003674 molecular_function*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005856 cytoskeleton*GO:0005886 plasma membrane*GO:0005911 intercellular junction*GO:0005912 adherens junction*GO:0005913 cell-cell adherens junction*GO:0005918 septate junction*GO:0006605 protein targeting*GO:0006612 protein-membrane targeting*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007043 intercellular junction assembly*GO:0007163 establishment and/or maintenance of cell polarity*GO:0007275 development*GO:0007391 dorsal closure*GO:0007431 salivary gland development*GO:0007435 salivary gland morphogenesis*GO:0007582 physiological process*GO:0007592 cuticle biosynthesis (sensu Protostomia and Nematoda)*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008362 embryonic cuticle biosynthesis (sensu Insecta)*GO:0009058 biosynthesis*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009795 embryonic morphogenesis*GO:0009887 organogenesis*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016020 membrane*GO:0016043 cell organization and biogenesis*GO:0016327 apicolateral plasma membrane*GO:0016331 morphogenesis of embryonic epithelium*GO:0019538 protein metabolism*GO:0019991 septate junction assembly*GO:0030054 cell junction*GO:0040003 cuticle biosynthesis (sensu Insecta)*GO:0042335 cuticle biosynthesis*GO:0043170 macromolecule metabolism*GO:0045216 intercellular junction assembly and/or maintenance*GO:0046907 intracellular transport*GO:0050875 cellular physiological process* REAL 10.61 10.61 1 CG11949-RD cora FBgn0010434 GO:0000902 cellular morphogenesis*GO:0001700 embryonic development (sensu Insecta)*GO:0002009 morphogenesis of an epithelium*GO:0003674 molecular_function*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005856 cytoskeleton*GO:0005886 plasma membrane*GO:0005911 intercellular junction*GO:0005912 adherens junction*GO:0005913 cell-cell adherens junction*GO:0005918 septate junction*GO:0006605 protein targeting*GO:0006612 protein-membrane targeting*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007043 intercellular junction assembly*GO:0007163 establishment and/or maintenance of cell polarity*GO:0007275 development*GO:0007391 dorsal closure*GO:0007431 salivary gland development*GO:0007435 salivary gland morphogenesis*GO:0007582 physiological process*GO:0007592 cuticle biosynthesis (sensu Protostomia and Nematoda)*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008362 embryonic cuticle biosynthesis (sensu Insecta)*GO:0009058 biosynthesis*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009795 embryonic morphogenesis*GO:0009887 organogenesis*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016020 membrane*GO:0016043 cell organization and biogenesis*GO:0016327 apicolateral plasma membrane*GO:0016331 morphogenesis of embryonic epithelium*GO:0019538 protein metabolism*GO:0019991 septate junction assembly*GO:0030054 cell junction*GO:0040003 cuticle biosynthesis (sensu Insecta)*GO:0042335 cuticle biosynthesis*GO:0043170 macromolecule metabolism*GO:0045216 intercellular junction assembly and/or maintenance*GO:0046907 intracellular transport*GO:0050875 cellular physiological process* REAL 10.61 10.61 1 CG11949-RA cora FBgn0010434 GO:0000902 cellular morphogenesis*GO:0001700 embryonic development (sensu Insecta)*GO:0002009 morphogenesis of an epithelium*GO:0003674 molecular_function*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005856 cytoskeleton*GO:0005886 plasma membrane*GO:0005911 intercellular junction*GO:0005912 adherens junction*GO:0005913 cell-cell adherens junction*GO:0005918 septate junction*GO:0006605 protein targeting*GO:0006612 protein-membrane targeting*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007043 intercellular junction assembly*GO:0007163 establishment and/or maintenance of cell polarity*GO:0007275 development*GO:0007391 dorsal closure*GO:0007431 salivary gland development*GO:0007435 salivary gland morphogenesis*GO:0007582 physiological process*GO:0007592 cuticle biosynthesis (sensu Protostomia and Nematoda)*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008362 embryonic cuticle biosynthesis (sensu Insecta)*GO:0009058 biosynthesis*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009795 embryonic morphogenesis*GO:0009887 organogenesis*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016020 membrane*GO:0016043 cell organization and biogenesis*GO:0016327 apicolateral plasma membrane*GO:0016331 morphogenesis of embryonic epithelium*GO:0019538 protein metabolism*GO:0019991 septate junction assembly*GO:0030054 cell junction*GO:0040003 cuticle biosynthesis (sensu Insecta)*GO:0042335 cuticle biosynthesis*GO:0043170 macromolecule metabolism*GO:0045216 intercellular junction assembly and/or maintenance*GO:0046907 intracellular transport*GO:0050875 cellular physiological process* REAL 10.61 10.61 1 CG14363-RA - FBgn0038185 - REAL 10.38 10.38 1 CG7672-RB gl FBgn0004618 GO:0000902 cellular morphogenesis*GO:0000904 cellular morphogenesis during differentiation*GO:0001654 eye morphogenesis*GO:0001745 compound eye morphogenesis (sensu Drosophila)*GO:0001751 eye photoreceptor differentiation (sensu Drosophila)*GO:0001754 eye photoreceptor cell differentiation*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0003700 transcription factor activity*GO:0003702 RNA polymerase II transcription factor activity*GO:0003704 specific RNA polymerase II transcription factor activity*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005634 nucleus*GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0006350 transcription*GO:0006351 transcription, DNA-dependent*GO:0006355 regulation of transcription, DNA-dependent*GO:0006357 regulation of transcription from Pol II promoter*GO:0006366 transcription from Pol II promoter*GO:0007275 development*GO:0007444 imaginal disc development*GO:0007452 imaginal disc metamorphosis*GO:0007455 eye-antennal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007459 photoreceptor fate commitment (sensu Drosophila)*GO:0007467 photoreceptor differentiation (sensu Drosophila)*GO:0007552 metamorphosis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008283 cell proliferation*GO:0008594 photoreceptor cell morphogenesis (sensu Drosophila)*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0009987 cellular process*GO:0016043 cell organization and biogenesis*GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0019222 regulation of metabolism*GO:0030154 cell differentiation*GO:0030528 transcription regulator activity*GO:0042051 eye photoreceptor development (sensu Drosophila)*GO:0042461 photoreceptor cell development*GO:0042462 eye photoreceptor cell development*GO:0045165 cell fate commitment*GO:0045449 regulation of transcription*GO:0046530 photoreceptor cell differentiation*GO:0046552 photoreceptor cell fate commitment*GO:0046698 metamorphosis (sensu Insecta)*GO:0048468 cell development*GO:0050789 regulation of biological process*GO:0050791 regulation of physiological process*GO:0050875 cellular physiological process*JU:0007444 transcription + imaginal disc development*JU:0001654 transcription + eye morphogenesis* REAL 10.38 10.38 1 CG31004-RA - FBgn0051004 - REAL 10.33 10.33 1 CG32379-RA - FBgn0052379 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0006508 proteolysis and peptidolysis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008233 peptidase activity*GO:0008237 metallopeptidase activity*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0016787 hydrolase activity*GO:0019538 protein metabolism*GO:0030163 protein catabolism*GO:0043170 macromolecule metabolism* REAL 10.33 10.33 1 CG11127-RA - FBgn0033178 - PRED 10.23 10.23 1 CG2762-RA ush FBgn0003963 GO:0000578 embryonic axis specification*GO:0001654 eye morphogenesis*GO:0001700 embryonic development (sensu Insecta)*GO:0001709 cell fate determination*GO:0002009 morphogenesis of an epithelium*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0003700 transcription factor activity*GO:0004871 signal transducer activity*GO:0004872 receptor activity*GO:0004879 ligand-dependent nuclear receptor activity*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005634 nucleus*GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0006350 transcription*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway*GO:0007275 development*GO:0007350 blastoderm segmentation*GO:0007351 regional subdivision*GO:0007354 zygotic determination of anterior/posterior axis, embryo*GO:0007362 terminal region determination*GO:0007389 pattern specification*GO:0007390 germ-band shortening*GO:0007391 dorsal closure*GO:0007392 initiation of dorsal closure*GO:0007393 dorsal closure, leading edge cell fate determination*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007507 heart development*GO:0007582 physiological process*GO:0008134 transcription factor binding*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008258 head involution*GO:0008293 torso signaling pathway*GO:0008595 determination of anterior/posterior axis, embryo*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009792 embryonic development (sensu Animalia)*GO:0009795 embryonic morphogenesis*GO:0009798 axis specification*GO:0009880 embryonic pattern specification*GO:0009887 organogenesis*GO:0009948 anterior/posterior axis specification*GO:0009952 anterior/posterior pattern formation*GO:0009987 cellular process*GO:0016331 morphogenesis of embryonic epithelium*GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0019222 regulation of metabolism*GO:0030097 hemopoiesis*GO:0030154 cell differentiation*GO:0030528 transcription regulator activity*GO:0030855 epithelial cell differentiation*GO:0035026 leading edge cell differentiation*GO:0035027 leading edge cell fate commitment*GO:0035028 leading edge cell fate determination*GO:0035029 dorsal closure, leading edge cell fate commitment*GO:0042386 hemocyte differentiation (sensu Arthropoda)*GO:0042440 pigment metabolism*GO:0042688 crystal cell differentiation*GO:0042689 regulation of crystal cell differentiation*GO:0042690 negative regulation of crystal cell differentiation*GO:0045165 cell fate commitment*GO:0045449 regulation of transcription*GO:0045595 regulation of cell differentiation*GO:0045596 negative regulation of cell differentiation*GO:0045610 regulation of hemocyte differentiation*GO:0045611 negative regulation of hemocyte differentiation*GO:0046663 dorsal closure, leading edge cell differentiation*GO:0046665 amnioserosa maintenance*GO:0048066 pigmentation*GO:0050789 regulation of biological process*GO:0050791 regulation of physiological process*GO:0050793 regulation of development*GO:0050794 regulation of cellular process*GO:0051093 negative regulation of development*JU:0030097 transcription + hemopoiesis*JU:0007507 transcription + heart development*JU:0001654 transcription + eye morphogenesis* REAL 9.97 9.97 1 CG2204-RB G-oalpha47A FBgn0001122 GO:0003927 heterotrimeric G-protein GTPase activity*GO:0005575 cellular_component*GO:0005623 cell*GO:0005834 heterotrimeric G-protein complex*GO:0005886 plasma membrane*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0007275 development*GO:0007507 heart development*GO:0008150 biological_process*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0009987 cellular process*GO:0016020 membrane*GO:0019897 extrinsic to plasma membrane*GO:0019898 extrinsic to membrane* REAL 9.89 9.89 1 CG9614-RK pip FBgn0003089 GO:0000003 reproduction*GO:0000279 M phase*GO:0000280 nuclear division*GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004394 heparin-sulfate 2-sulfotransferase activity*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005634 nucleus*GO:0005694 chromosome*GO:0005737 cytoplasm*GO:0005794 Golgi apparatus*GO:0006464 protein modification*GO:0007049 cell cycle*GO:0007126 meiosis*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007275 development*GO:0007276 gametogenesis*GO:0007292 female gamete generation*GO:0007308 oocyte construction*GO:0007309 oocyte axis determination*GO:0007310 oocyte dorsal/ventral axis determination*GO:0007313 maternal determination of dorsal/ventral axis, oocyte, soma encoded*GO:0007389 pattern specification*GO:0007582 physiological process*GO:0008063 Toll signaling pathway*GO:0008146 sulfotransferase activity*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0008283 cell proliferation*GO:0009798 axis specification*GO:0009950 dorsal/ventral axis specification*GO:0009953 dorsal/ventral pattern formation*GO:0009987 cellular process*GO:0009993 oogenesis (sensu Insecta)*GO:0016485 protein processing*GO:0016740 transferase activity*GO:0016782 transferase activity, transferring sulfur-containing groups*GO:0019538 protein metabolism*GO:0019953 sexual reproduction*GO:0043170 macromolecule metabolism*GO:0048477 oogenesis*GO:0050875 cellular physiological process* PRED 9.89 9.89 1 CG3954-RB csw FBgn0000382 GO:0000003 reproduction*GO:0000578 embryonic axis specification*GO:0001654 eye morphogenesis*GO:0001745 compound eye morphogenesis (sensu Drosophila)*GO:0001751 eye photoreceptor differentiation (sensu Drosophila)*GO:0001752 eye photoreceptor fate commitment (sensu Drosophila)*GO:0001754 eye photoreceptor cell differentiation*GO:0002009 morphogenesis of an epithelium*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004721 phosphoprotein phosphatase activity*GO:0004725 protein tyrosine phosphatase activity*GO:0004726 non-membrane spanning protein tyrosine phosphatase activity*GO:0004728 receptor signaling protein tyrosine phosphatase activity*GO:0004871 signal transducer activity*GO:0005057 receptor signaling protein activity*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0006464 protein modification*GO:0006470 protein amino acid dephosphorylation*GO:0006793 phosphorus metabolism*GO:0006796 phosphate metabolism*GO:0006928 cell motility*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway*GO:0007173 epidermal growth factor receptor signaling pathway*GO:0007275 development*GO:0007276 gametogenesis*GO:0007292 female gamete generation*GO:0007350 blastoderm segmentation*GO:0007351 regional subdivision*GO:0007354 zygotic determination of anterior/posterior axis, embryo*GO:0007362 terminal region determination*GO:0007389 pattern specification*GO:0007399 neurogenesis*GO:0007417 central nervous system development*GO:0007418 ventral midline development*GO:0007424 tracheal system development (sensu Insecta)*GO:0007427 tracheal cell migration (sensu Insecta)*GO:0007444 imaginal disc development*GO:0007452 imaginal disc metamorphosis*GO:0007455 eye-antennal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007459 photoreceptor fate commitment (sensu Drosophila)*GO:0007465 R7 cell fate commitment*GO:0007467 photoreceptor differentiation (sensu Drosophila)*GO:0007498 mesoderm development*GO:0007552 metamorphosis*GO:0007582 physiological process*GO:0008069 dorsal/ventral axis determination, follicular epithelium (sensu Insecta)*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008293 torso signaling pathway*GO:0008543 fibroblast growth factor receptor signaling pathway*GO:0008595 determination of anterior/posterior axis, embryo*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009798 axis specification*GO:0009880 embryonic pattern specification*GO:0009887 organogenesis*GO:0009888 histogenesis*GO:0009948 anterior/posterior axis specification*GO:0009950 dorsal/ventral axis specification*GO:0009952 anterior/posterior pattern formation*GO:0009953 dorsal/ventral pattern formation*GO:0009987 cellular process*GO:0009993 oogenesis (sensu Insecta)*GO:0016311 dephosphorylation*GO:0016333 morphogenesis of follicular epithelium*GO:0016334 establishment and/or maintenance of polarity of follicular epithelium*GO:0016477 cell migration*GO:0016787 hydrolase activity*GO:0016788 hydrolase activity, acting on ester bonds*GO:0016791 phosphoric monoester hydrolase activity*GO:0019538 protein metabolism*GO:0019953 sexual reproduction*GO:0030154 cell differentiation*GO:0030707 ovarian follicle cell development (sensu Insecta)*GO:0042578 phosphoric ester hydrolase activity*GO:0042706 eye photoreceptor cell fate commitment*GO:0043170 macromolecule metabolism*GO:0045165 cell fate commitment*GO:0045466 R7 differentiation*GO:0045500 sevenless signaling pathway*GO:0046530 photoreceptor cell differentiation*GO:0046552 photoreceptor cell fate commitment*GO:0046698 metamorphosis (sensu Insecta)*GO:0048477 oogenesis*GO:0050875 cellular physiological process*KEGG:17.4 Phosphatidylinositol signaling system* REAL 9.83 9.83 1 CG13489-RA - FBgn0034672 - PRED 9.83 9.83 1 CG3732-RA - FBgn0034750 GO:0003674 molecular_function*GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism*GO:0006350 transcription*GO:0006351 transcription, DNA-dependent*GO:0006366 transcription from Pol II promoter*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0030528 transcription regulator activity* REAL 9.83 9.83 1 CG2774-RA - FBgn0031534 GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006897 endocytosis*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016192 vesicle-mediated transport*GO:0046907 intracellular transport*GO:0050875 cellular physiological process* REAL 9.83 9.83 1 CG17855-RA - FBgn0032124 - PRED 9.83 9.83 1 CG13134-RA - FBgn0032182 - PRED 9.83 9.83 1 CG33116-RA - FBgn0053116 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0006629 lipid metabolism*GO:0006643 membrane lipid metabolism*GO:0006644 phospholipid metabolism*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008414 CDP-alcohol phosphotransferase activity*GO:0016740 transferase activity* REAL 9.83 9.83 1 CG15695-RA - FBgn0038832 - REAL 9.83 9.83 1 CG6454-RA - FBgn0039187 - REAL 9.83 9.83 1 CG5789-RA - FBgn0039207 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004009 ATP-binding cassette (ABC) transporter activity*GO:0005215 transporter activity*GO:0005386 carrier activity*GO:0006810 transport*GO:0006858 extracellular transport*GO:0006952 defense response*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008559 xenobiotic-transporting ATPase activity*GO:0009605 response to external stimulus*GO:0009607 response to biotic stimulus*GO:0009628 response to abiotic stimulus*GO:0009636 response to toxin*GO:0009987 cellular process*GO:0015238 drug transporter activity*GO:0015239 multidrug transporter activity*GO:0015399 primary active transporter activity*GO:0015405 P-P-bond-hydrolysis-driven transporter activity*GO:0015427 ABC-type efflux porter activity*GO:0016787 hydrolase activity*GO:0016817 hydrolase activity, acting on acid anhydrides*GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides*GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances*GO:0016887 ATPase activity*GO:0042221 response to chemical substance*GO:0042623 ATPase activity, coupled*GO:0042626 ATPase activity, coupled to transmembrane movement of substances*GO:0050875 cellular physiological process*GO:0050896 response to stimulus* REAL 9.83 9.83 1 CG13976-RA Gr98a FBgn0039520 GO:0001584 rhodopsin-like receptor activity*GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0004872 receptor activity*GO:0004888 transmembrane receptor activity*GO:0004930 G-protein coupled receptor activity*GO:0007582 physiological process*GO:0007600 sensory perception*GO:0007606 sensory perception of chemical stimulus*GO:0008150 biological_process*GO:0008527 taste receptor activity*GO:0009581 detection of external stimulus*GO:0009605 response to external stimulus*GO:0050874 organismal physiological process*GO:0050877 neurophysiological process*GO:0050896 response to stimulus*GO:0050909 perception of taste* PRED 9.83 9.83 1 CG12558-RA - FBgn0039599 - PRED 9.83 9.83 1 CG1044-RA dos FBgn0016794 GO:0000578 embryonic axis specification*GO:0001654 eye morphogenesis*GO:0001745 compound eye morphogenesis (sensu Drosophila)*GO:0001751 eye photoreceptor differentiation (sensu Drosophila)*GO:0001752 eye photoreceptor fate commitment (sensu Drosophila)*GO:0001754 eye photoreceptor cell differentiation*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0005057 receptor signaling protein activity*GO:0005066 transmembrane receptor protein tyrosine kinase signaling protein activity*GO:0005069 transmembrane receptor protein tyrosine kinase docking protein activity*GO:0005070 SH3/SH2 adaptor protein activity*GO:0005575 cellular_component*GO:0005623 cell*GO:0005886 plasma membrane*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007167 enzyme linked receptor protein signaling pathway*GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway*GO:0007275 development*GO:0007350 blastoderm segmentation*GO:0007351 regional subdivision*GO:0007389 pattern specification*GO:0007444 imaginal disc development*GO:0007452 imaginal disc metamorphosis*GO:0007455 eye-antennal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007459 photoreceptor fate commitment (sensu Drosophila)*GO:0007465 R7 cell fate commitment*GO:0007467 photoreceptor differentiation (sensu Drosophila)*GO:0007552 metamorphosis*GO:0008150 biological_process*GO:0008293 torso signaling pathway*GO:0008595 determination of anterior/posterior axis, embryo*GO:0009653 morphogenesis*GO:0009790 embryonic development*GO:0009798 axis specification*GO:0009880 embryonic pattern specification*GO:0009887 organogenesis*GO:0009948 anterior/posterior axis specification*GO:0009952 anterior/posterior pattern formation*GO:0009987 cellular process*GO:0016020 membrane*GO:0030154 cell differentiation*GO:0042706 eye photoreceptor cell fate commitment*GO:0045165 cell fate commitment*GO:0045466 R7 differentiation*GO:0045500 sevenless signaling pathway*GO:0046530 photoreceptor cell differentiation*GO:0046552 photoreceptor cell fate commitment*GO:0046698 metamorphosis (sensu Insecta)* REAL 9.83 9.83 1 CG6327-RA - FBgn0036115 - REAL 9.83 9.83 1 CG13244-RA - FBgn0032577 - REAL 9.82 9.82 1 CG31308-RA - FBgn0051308 - PRED 9.73 9.73 1 CG9446-RA coro FBgn0033109 GO:0003674 molecular_function*GO:0003779 actin binding*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005856 cytoskeleton*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007582 physiological process*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009987 cellular process*GO:0015629 actin cytoskeleton*GO:0016043 cell organization and biogenesis*GO:0050875 cellular physiological process* REAL 9.71 9.71 1 CG1708-RA cos FBgn0000352 GO:0000003 reproduction*GO:0003674 molecular_function*GO:0003774 motor activity*GO:0003777 microtubule motor activity*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0005856 cytoskeleton*GO:0005871 kinesin complex*GO:0005875 microtubule associated complex*GO:0006508 proteolysis and peptidolysis*GO:0006605 protein targeting*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007017 microtubule-based process*GO:0007018 microtubule-based movement*GO:0007028 cytoplasm organization and biogenesis*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007224 smoothened receptor signaling pathway*GO:0007275 development*GO:0007276 gametogenesis*GO:0007292 female gamete generation*GO:0007582 physiological process*GO:0008017 microtubule binding*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0009894 regulation of catabolism*GO:0009987 cellular process*GO:0009993 oogenesis (sensu Insecta)*GO:0015031 protein transport*GO:0015630 microtubule cytoskeleton*GO:0015631 tubulin binding*GO:0016043 cell organization and biogenesis*GO:0019222 regulation of metabolism*GO:0019538 protein metabolism*GO:0019953 sexual reproduction*GO:0030162 regulation of proteolysis and peptidolysis*GO:0030163 protein catabolism*GO:0030705 cytoskeleton-dependent intracellular transport*GO:0030707 ovarian follicle cell development (sensu Insecta)*GO:0043170 macromolecule metabolism*GO:0046907 intracellular transport*GO:0048477 oogenesis*GO:0050789 regulation of biological process*GO:0050791 regulation of physiological process*GO:0050875 cellular physiological process*KEGG:22.1 Wnt signaling pathway* REAL 9.71 9.71 1 CG2519-RA - FBgn0037336 - REAL 9.71 9.71 1 CG6863-RB tok FBgn0004885 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004175 endopeptidase activity*GO:0004222 metalloendopeptidase activity*GO:0006508 proteolysis and peptidolysis*GO:0007275 development*GO:0007389 pattern specification*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008152 metabolism*GO:0008233 peptidase activity*GO:0008237 metallopeptidase activity*GO:0009056 catabolism*GO:0009057 macromolecule catabolism*GO:0009798 axis specification*GO:0009950 dorsal/ventral axis specification*GO:0009953 dorsal/ventral pattern formation*GO:0016787 hydrolase activity*GO:0017026 procollagen C-endopeptidase activity*GO:0019538 protein metabolism*GO:0030163 protein catabolism*GO:0043170 macromolecule metabolism* REAL 9.71 9.71 1 CG32140-RA - FBgn0052140 - PRED 9.71 9.71 1 CG6355-RA EG:52C10.5 FBgn0028741 GO:0001727 lipid kinase activity*GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004428 inositol or phosphatidylinositol kinase activity*GO:0006793 phosphorus metabolism*GO:0006796 phosphate metabolism*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016301 kinase activity*GO:0016307 phosphatidylinositol phosphate kinase activity*GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity*GO:0016310 phosphorylation*GO:0016740 transferase activity*GO:0016772 transferase activity, transferring phosphorus-containing groups*GO:0016773 phosphotransferase activity, alcohol group as acceptor*GO:0046907 intracellular transport*GO:0050875 cellular physiological process*KEGG:8.3 Inositol phosphate metabolism*KEGG:17.4 Phosphatidylinositol signaling system* REAL 9.68 9.68 1 CG6822-RA rhea FBgn0020254 GO:0003674 molecular_function*GO:0003779 actin binding*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005623 cell*GO:0005886 plasma membrane*GO:0005912 adherens junction*GO:0005924 cell-substrate adherens junction*GO:0005925 focal adhesion*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006928 cell motility*GO:0006952 defense response*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007016 cytoskeletal anchoring*GO:0007028 cytoplasm organization and biogenesis*GO:0007154 cell communication*GO:0007155 cell adhesion*GO:0007582 physiological process*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009607 response to biotic stimulus*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016020 membrane*GO:0016043 cell organization and biogenesis*GO:0016327 apicolateral plasma membrane*GO:0016343 cytoskeletal anchoring activity*GO:0030054 cell junction*GO:0030055 cell-matrix junction*GO:0046907 intracellular transport*GO:0050875 cellular physiological process*GO:0050896 response to stimulus* REAL 9.58 9.58 1 CG6822-RB rhea FBgn0020254 GO:0003674 molecular_function*GO:0003779 actin binding*GO:0005198 structural molecule activity*GO:0005200 structural constituent of cytoskeleton*GO:0005488 binding*GO:0005515 protein binding*GO:0005575 cellular_component*GO:0005623 cell*GO:0005886 plasma membrane*GO:0005912 adherens junction*GO:0005924 cell-substrate adherens junction*GO:0005925 focal adhesion*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006928 cell motility*GO:0006952 defense response*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007016 cytoskeletal anchoring*GO:0007028 cytoplasm organization and biogenesis*GO:0007154 cell communication*GO:0007155 cell adhesion*GO:0007582 physiological process*GO:0008092 cytoskeletal protein binding*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009607 response to biotic stimulus*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016020 membrane*GO:0016043 cell organization and biogenesis*GO:0016327 apicolateral plasma membrane*GO:0016343 cytoskeletal anchoring activity*GO:0030054 cell junction*GO:0030055 cell-matrix junction*GO:0046907 intracellular transport*GO:0050875 cellular physiological process*GO:0050896 response to stimulus* REAL 9.58 9.58 1 CG4620-RA unk FBgn0004395 GO:0001654 eye morphogenesis*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0007275 development*GO:0007399 neurogenesis*GO:0007422 peripheral nervous system development*GO:0007423 sensory organ development*GO:0007444 imaginal disc development*GO:0007452 imaginal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007472 wing disc metamorphosis*GO:0007476 wing morphogenesis*GO:0007552 metamorphosis*GO:0008150 biological_process*GO:0008270 zinc ion binding*GO:0008407 bristle morphogenesis*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0035107 appendage morphogenesis*GO:0035114 appendage morphogenesis (sensu Holometabola)*GO:0043167 ion binding*GO:0046698 metamorphosis (sensu Insecta)*GO:0046872 metal ion binding*GO:0046914 transition metal ion binding* REAL 9.52 9.52 1 CG4620-RB unk FBgn0004395 GO:0001654 eye morphogenesis*GO:0002164 larval development*GO:0002165 larval or pupal development (sensu Insecta)*GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003677 DNA binding*GO:0005488 binding*GO:0005575 cellular_component*GO:0005622 intracellular*GO:0005623 cell*GO:0005737 cytoplasm*GO:0007275 development*GO:0007399 neurogenesis*GO:0007422 peripheral nervous system development*GO:0007423 sensory organ development*GO:0007444 imaginal disc development*GO:0007452 imaginal disc metamorphosis*GO:0007456 eye morphogenesis (sensu Drosophila)*GO:0007472 wing disc metamorphosis*GO:0007476 wing morphogenesis*GO:0007552 metamorphosis*GO:0008150 biological_process*GO:0008270 zinc ion binding*GO:0008407 bristle morphogenesis*GO:0009653 morphogenesis*GO:0009887 organogenesis*GO:0035107 appendage morphogenesis*GO:0035114 appendage morphogenesis (sensu Holometabola)*GO:0043167 ion binding*GO:0046698 metamorphosis (sensu Insecta)*GO:0046872 metal ion binding*GO:0046914 transition metal ion binding* REAL 9.52 9.52 1 CG31848-RA - FBgn0051848 GO:0000004 biological_process unknown*GO:0003674 molecular_function*GO:0005554 molecular_function unknown*GO:0005575 cellular_component*GO:0008150 biological_process*GO:0008372 cellular_component unknown* PRED 9.46 9.46 1 CG10492-RA - FBgn0032748 - REAL 9.46 9.46 1 CG11672-RA - FBgn0037563 - REAL 9.46 9.46 1 CG31437-RA - FBgn0051437 GO:0000004 biological_process unknown*GO:0003674 molecular_function*GO:0005554 molecular_function unknown*GO:0005575 cellular_component*GO:0008150 biological_process*GO:0008372 cellular_component unknown* PRED 9.46 9.46 1 CG1800-RA - FBgn0039861 GO:0003674 molecular_function*GO:0003676 nucleic acid binding*GO:0003723 RNA binding*GO:0003725 double-stranded RNA binding*GO:0005488 binding* REAL 9.46 9.46 1 CG14743-RA - FBgn0033326 - PRED 8.07 8.07 1 CG6805-RA - FBgn0034179 GO:0003674 molecular_function*GO:0003824 catalytic activity*GO:0004437 inositol or phosphatidylinositol phosphatase activity*GO:0006629 lipid metabolism*GO:0006793 phosphorus metabolism*GO:0006796 phosphate metabolism*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007242 intracellular signaling cascade*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0009987 cellular process*GO:0016043 cell organization and biogenesis*GO:0016311 dephosphorylation*GO:0016787 hydrolase activity*GO:0016788 hydrolase activity, acting on ester bonds*GO:0016791 phosphoric monoester hydrolase activity*GO:0019722 calcium-mediated signaling*GO:0019932 second-messenger-mediated signaling*GO:0042578 phosphoric ester hydrolase activity*GO:0046030 inositol trisphosphate phosphatase activity*GO:0050875 cellular physiological process* REAL 7.99 7.99 1 CG32779-RA - FBgn0052779 - PRED 7.28 7.28 1 CG11347-RD - FBgn0035542 - REAL 7.05 7.05 1 CG3320-RB Rab1 FBgn0016700 GO:0003925 small monomeric GTPase activity*GO:0003928 RAB small monomeric GTPase activity*GO:0003931 Rho small monomeric GTPase activity*GO:0006810 transport*GO:0006886 intracellular protein transport*GO:0006887 exocytosis*GO:0006888 ER to Golgi transport*GO:0006897 endocytosis*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009987 cellular process*GO:0015031 protein transport*GO:0016192 vesicle-mediated transport*GO:0017157 regulation of exocytosis*GO:0045045 secretory pathway*GO:0046907 intracellular transport*GO:0048193 Golgi vesicle transport*GO:0050789 regulation of biological process*GO:0050794 regulation of cellular process*GO:0050875 cellular physiological process*GO:0051049 regulation of transport* REAL 6.54 6.54 1 CG4468-RA - FBgn0038749 - REAL 6.53 6.53 1 CG32447-RA - FBgn0052447 GO:0003674 molecular_function*GO:0004871 signal transducer activity*GO:0004872 receptor activity*GO:0004888 transmembrane receptor activity*GO:0004930 G-protein coupled receptor activity*GO:0005575 cellular_component*GO:0005623 cell*GO:0007154 cell communication*GO:0007165 signal transduction*GO:0007166 cell surface receptor linked signal transduction*GO:0007186 G-protein coupled receptor protein signaling pathway*GO:0007215 glutamate signaling pathway*GO:0007216 metabotropic glutamate receptor signaling pathway*GO:0008066 glutamate receptor activity*GO:0008067 metabotropic glutamate, GABA-B-like receptor activity*GO:0008150 biological_process*GO:0009987 cellular process*GO:0016020 membrane*GO:0016021 integral to membrane* REAL 6.23 6.23 1 CG13353-RA - FBgn0033896 - PRED 6.04 6.04 1 CG33171-RE - FBgn0053171 GO:0003674 molecular_function*GO:0005198 structural molecule activity*GO:0005201 extracellular matrix structural constituent*GO:0005575 cellular_component*GO:0005576 extracellular*GO:0005578 extracellular matrix*GO:0005581 collagen*GO:0006996 organelle organization and biogenesis*GO:0007010 cytoskeleton organization and biogenesis*GO:0007028 cytoplasm organization and biogenesis*GO:0007154 cell communication*GO:0007155 cell adhesion*GO:0007160 cell-matrix adhesion*GO:0007165 signal transduction*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0009987 cellular process*GO:0016043 cell organization and biogenesis*GO:0050875 cellular physiological process* REAL 5.78 5.78 1 CG30381-RA - FBgn0050381 GO:0000004 biological_process unknown*GO:0003674 molecular_function*GO:0005554 molecular_function unknown*GO:0005575 cellular_component*GO:0008150 biological_process*GO:0008372 cellular_component unknown* PRED 5.77 5.77 1 CG12317-RB JhI-21 FBgn0028425 GO:0003674 molecular_function*GO:0005215 transporter activity*GO:0005275 amine transporter activity*GO:0005342 organic acid transporter activity*GO:0006082 organic acid metabolism*GO:0006519 amino acid and derivative metabolism*GO:0006520 amino acid metabolism*GO:0006810 transport*GO:0006865 amino acid transport*GO:0007582 physiological process*GO:0008150 biological_process*GO:0008151 cell growth and/or maintenance*GO:0008152 metabolism*GO:0009308 amine metabolism*GO:0009987 cellular process*GO:0015171 amino acid transporter activity*GO:0015179 L-amino acid transporter activity*GO:0015837 amine transport*GO:0015849 organic acid transport*GO:0019752 carboxylic acid metabolism*GO:0046942 carboxylic acid transport*GO:0046943 carboxylic acid transporter activity*GO:0050875 cellular physiological process* REAL 4.54 4.54 1